Abstract: The freedom of research is a cornerstone of our civilisation; in many ways it can even be seen as a human right. However, freedom of research does not mean the liberty to cheat. Cheating in science – deliberate falsification of evidence to support a hypothesis – is not only academic misconduct; it is also a crime against society and the truth. This article sets the bold road map for honest and radical proceedings aiming to mitigate the replication crisis