• OBSERVATIONAL STUDY ON CLINICAL FEATURES, TREATMENT AND OUTCOME OF COVID 19 IN A TERTIARY CARE CENTRE IN INDIA - A RETROSPECTIVE CASE SERIES

    Author(s):
    Rishav Mukherjee (see profile)
    Date:
    2020
    Subject(s):
    Medicine
    Item Type:
    Article
    Tag(s):
    infectious disease
    Permanent URL:
    http://dx.doi.org/10.17613/kys5-2f72
    Abstract:
    Till date, no proven therapy exists for treatment of SARS-coV-2 infections which has been declared a pandemic by WHO in March, 2020. OBJECTIVE: This study will attempt to explore the demographic prole and outcome in the patients receiving multidisciplinary, personalised approach including use of Broad Spectrum Antivirals - Ivermectin, anti-inammatory and antioxidants roles of Statins and N-acetyl-cysteine along with Standard of Care (SOC) in hospitalised COVID19 patients in a tertiary care centre. SETTING: Inpatient department (designated COVID ward) PARTICIPANTS: COVID-19 patients with laboratory conrmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in the year 2020 between June 14- 28, 2020 Main outcome measures: The outcome of Interests are : a. Studying the demographic prole of COVID 19 cases b. Study the treatment outcomes in terms of death or discharge in patients receiving Ivermectin+N-acetyl-cysteine+Statin along with Standard of care.RESULTS: 148 patients were included in the study. All of them had conrmed COVID19 infection by the rtPCR method. Average age of the patients was 57.57 years ( Range = 17 - 88), 49% were male, 51% female. 81% of the patients had at least one or more comorbidities. Most common comorbidities included diabetes( 32%), Hypertension (27%),Ischaemic Heart Disease (8%). More comorbidities. The in hospital, Case Fatality Rate was 1.35 %. The remaining 146 were discharged from the facility after an average 12 days duration of stay. CONCLUSIONS:. Triple therapy with Ivermectin, N-acetyl-cysteine and Atorvastatin along with standard of care is safe and effective in SARS- coV-2 infection.
    Metadata:
    Published as:
    Journal article    
    Status:
    Pending Review
    Last Updated:
    2 years ago
    License:
    All Rights Reserved

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